Cases of neurofibromata (pseudo-neuromata, solitary neuromata) of the orbit are extremely rare, there being but two cases on record. Of these, one reported by Tersch1 involved the lachrymal branch, and one reported by Marchetti2 the infraorbital branch of the fifth nerve.
The ophthalmic division of the fifth nerve has been involved in multiple neuromata, and Bietti3 has described amputation neuromata of the ciliary nerves after optic-ciliary-neurotomy. Houel4 has described small tumors of the third, fourth, nasal and frontal branches of the fifth nerve, found postmortem, which had never caused clinical symptoms.
The extreme rarity of neurofibromata is shown by the following statement of Tersch: "A solitary neuroma is altogether a rare tumor and its location in the orbit appears at least a curiosity;" and of Marchetti, who, after eliminating the plexiform neuromata as described by Billroth and others, says: "The exposition of the case shows its
PARKER WR. NEUROFIBROMA OF THE ORBIT: KRÖNLEIN OPERATION.. JAMA. 1907;XLIX(1):17-19. doi:10.1001/jama.1907.25320010017002d