August 18, 1917


Author Affiliations

Fellow of the American College of Surgeons FORT WAYNE, IND.

JAMA. 1917;LXIX(7):518-521. doi:10.1001/jama.1917.02590340018005

What is the function of the gallbladder, and of how much importance is it to the human economy? This is the paramount question that presents itself in a discussion of the relative merits of cholecystectomy and cholecystostomy. Man does not need bile in the intestine except when digestion is going on. During the period that the bile remains in the gallbladder it undergoes important changes, as is shown by comparison of the bile obtained from the gallbladder and that obtained from the bile ducts. During its stay in the gallbladder the bile has added to it mucin or nuclear albumin, and what is of much greater importance during its stay in the gallbladder, the bile has added to it sodium glycocholate and taurocholate. According to the tables of Yeo and Herroun and Hoppe-Seyler,1 this gain of the combined salts amounts to 3.69 parts in 100 parts of bile. The

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