[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.94.5. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
April 28, 1917

THE ABSORPTION OF APOMORPHIN AND MORPHIN THROUGH THE CONJUNCTIVA

Author Affiliations

BALTIMORE

From the Pharmacological Laboratory, Johns Hopkins University.

JAMA. 1917;LXVIII(17):1230. doi:10.1001/jama.1917.04270040218003
Abstract

While surgeons, gynecologists, and even authorities on internal medicine have on frequent occasions looked with little faith on the efficiency of drug medication, an attitude of drug nihilism cannot be imputed to the ophthalmologist. Indeed, some of the most important pharmacologic contributions have been in the field of ophthalmology, and some of the most strikingly beneficial therapeutic effects have been produced in the treatment of eye conditions. We need but mention the employment of atropin, cocain, physostigmin, epinephrin and many other mydriatics, miotics, astringents, analgesics and antiseptics.

When we consider the highly developed blood and lymph supply of the eye and its appendages, especially the patent tear ducts, it is surprising that so few cases of drug absorption and intoxication through them are on record. So few are the cases found in the literature that many physicians deny the possibility of such absorption through the conjunctiva and the lacrimal apparatus,

First Page Preview View Large
First page PDF preview
First page PDF preview
×