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Article
April 28, 1917

THE RELATION BETWEEN DIABETES MELLITUS AND CLINICAL SYPHILIS

Author Affiliations

PITTSBURGH

JAMA. 1917;LXVIII(17):1232-1234. doi:10.1001/jama.1917.04270040220005
Abstract

The recent work of Warthin and Wilson1 has stimulated interest in the question of coincidence of latent syphilis and diabetes. They report that in six necropsies in cases of diabetes, all presented histologic changes of syphilis; in four of them, spirochetes were found in the myocardium, and in one of these cases, in the pancreatic lesions. They also report that the pancreas in forty-one cases of latent syphilis already reported by Warthin2 showed marked changes, and conclude that "latent syphilis" is the chief factor in the production of the form of pancreatitis most frequently associated with diabetes, but that diabetes is not always coincident with severe degrees of this type of pancreatitis.

For several years, I have been interested in the possible relationships between clinically demonstrative syphilis and diabetes, and have studied the cases of diabetes encountered in practice in regard to this relationship. The data are presented

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