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D. R. T., man, aged 31, mill hand, married, first came under my care early in June, 1916, with symptoms of nephritis which readily improved under treatment. June 15, I was called to see him and found him suffering with acute appendicitis, for which he was immediately removed to a hospital and operated on.
August 15, he came to my office complaining of burning and itching of the scrotum. Examination revealed an intense reddening and slight thickening over an area about an inch in diameter on each side of the lower portion of the front of the scrotum. It was separated by a longitudinal strip of normal skin along the median raphe, and the erythematous area on the right side was somewhat larger and more intensified than that on the left. The junction of the reddened area with the normal adjacent skin formed a distinct line of demarcation, the two
Crosby CE. PELLAGRA WITH ERYTHEMA OF SCROTUM AS INITIAL SKIN MANIFESTATION. JAMA. 1917;LXVIII(19):1403-1404. doi:10.1001/jama.1917.04270050105009