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May 19, 1917


Author Affiliations

New Haven, Conn.

JAMA. 1917;LXVIII(20):1475. doi:10.1001/jama.1917.04270050177010

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T. Z. Cason, M.D., and E. G. Birge, M.D., Jacksonville, Fla,

This case of pernicious malaria presented several interesting features, particularly the blood picture and the reaction to treatment. Occasionally one obtains a picture of pernicious anemia in these cases, and the absence of parasites in the peripheral circulation throws the diagnosis in doubt unless a complete and careful study of the blood is made during the disease.

Treatment with quinin, properly given, promptly relieves the condition, and the improvement which takes place in the blood picture is surprising.

History.  —G. W., man, aged 33, white, farmer, was admitted to St. Luke's Hospital, Jacksonville, Fla., Jan. 16, 1917, in a comatose condition. The abdomen was distended and tympanitic. Physical examination at this time was negative. The family and personal history were unimportant. The Patient had been taken ill in October, and had had occasional headaches since. There was edema around

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