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Article
June 16, 1917

THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1917;LXVIII(24):1818-1821. doi:10.1001/jama.1917.04270060226014
Abstract

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SATURDAY, JUNE 16, 1917 

THE EXPERIMENTAL PRODUCTION OF CANCER  It has long been evident that many questions concerning the etiology of cancer would not be answered until this disease could be produced experimentally at will. This accomplishment would make possible the study of the development of the growth step by step, the determination of the factors necessary to incite malignant proliferation, and, evidently, the simultaneous exclusion of unessential or unimportant possible factors. In view of the importance of the subject, it would seem that surprisingly little systematic attempt has been made to accomplish the experimental production of cancer, as far as the literature shows; but it is probable that many more or less extensive experi

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