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August 31, 1907


JAMA. 1907;XLIX(9):789. doi:10.1001/jama.1907.02530090065019

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Philadelphia, Aug. 24, 1907.

To the Editor:  —The report on Probilin in The Journal, August 24, explains my experience with the formula suggested by Dr. R. W. Wilcox in his article on "The Medical Treatment of Gallstone Disease" (The Journal A. M. A., Aug. 4, 1906, page 347). Being desirous of carrying out the treatment suggested by Dr. Wilcox, I prescribed the formula of phenolphthalein with acid sodium oleate and salicylic acid. The pharmacist to whom the prescription was submitted informed me that it could not be compounded as written, but that he could dispense the materials massed separately in a capsule. Subsequently the same pharmacist suggested the use of sodium salicylate in place of the salicylic acid, the following modified formula being prescribed:Sodium oleate.... 0.10Sodium salicylate.... 0.10Phenolphthaalein.... 0.05Menthol.... 0.015Mix and dispense in 1 capsule.The sodium oleate was prepared by mixing the proper pro

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