Involvement of the cornea in the secondary stage of syphilis is not referred to in the literature as a possibility. Its neighboring structure, the conjunctiva bulbi, in a few instances, has been found involved in the secondary manifestations of this disease, but such involvement is of the greatest rarity, a careful search of the literature revealing records of only a few such cases. Recently, in my service at the Cook County Hospital, I had a case showing secondary syphilitic pustular eruptions involving the cornea and the conjunctiva of the globe and lids.
—T. O., aged 22, male, a porter by occupation, was admitted to the dermatologic division of Cook County Hospital April 19, 1905, where the diagnosis of syphilis in the secondary stage, which was made at the receiving room, was confirmed by the attending dermatologist, Dr. William Allen Pusey. On the following day, because of the eye conditions,
PUSEY B. INVOLVEMENT OF THE CORNEA AND BULBAR CONJUNCTIVA IN THE SECONDARY STAGE OF SYPHILIS.. JAMA. 1907;XLIX(10):828-829. doi:10.1001/jama.1907.25320100016001e