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—A girl, aged 4, was brought from an orphanage to the City and County Hospital, Sept. 7, 1916, for the purpose of having her tonsils and adenoids removed. One of the sisters in the orphanage had noticed that the child's eyes were getting larger and more prominent. An oculist who examined the child's eyes made little of the condition, and advised removal of the child's tonsils and adenoids, which was done.Several days after the operation, the child contracted chickcnpox, from which she recovered several days later. The physician in charge noticed that her eyes gradually became more prominent. For a time, it looked as though the exophthalmic condition was stationary, but later exophthalmos became more marked, the head became larger, and the nose became saddle-shapped. Examination of the eyes revealed choked disk. Exophthalmos of the eyes and enlargement of the head gradually increased, the glands of the neck
Kramer GB, Birnberg TL. REPORT OF A CASE OF CHLOROMA. JAMA. 1917;LXVIII(25):1900-1901. doi:10.1001/jama.1917.04270060308011