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September 7, 1907


JAMA. 1907;XLIX(10):854-855. doi:10.1001/jama.1907.02530100042005

The remarkable amount of work which has been done on the cerebrospinal fluid in the past few years may be imagined when it is stated that Kaupe was able to find references to 487 articles bearing on the subject published during the last three years. It is only since 1901, as Cornell1 points out, that lumbar puncture has been generally used by the neurologist and the psychiatrist, though the worth of the procedure was pointed out by Quincke ten years previously. It is fair to state, however, that since Quincke's original work considerable modifications in the methods of examination have come into vogue, so that at present an examination of the spinal fluid usually consists of a cyto-count, an estimation of the pressure of the fluid, and a determination of the proteid content. Of these three procedures the cyto-count, which includes an estimate of both the number and variety

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