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The idea that a disease, one attack of which is well known not to destroy susceptibility to future attacks, can be prevented by inoculation with any possible preparation of its efficient or specific cause, is so contrary to the simplest rules of induction, or, in other words, to "common sense," that one feels a degree of surprise that any intelligent medical man should waste his time in experimenting on the subject. But it appears that nothing is so extravagant or absurd, especially if connected with the modern germ theories of disease, but that it may find advocates willing to experiment wherever they can find deluded subjects willing to be used for that purpose. That one attack of genuine epidemic cholera does not afford the individual immunity from subsequent attacks of the same disease is well known to all who have had practical experience with the disease. A correspondent of the
CHOLERA INOCULATION.. JAMA. 1885;V(4):103-104. doi:10.1001/jama.1885.04470020019005