[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 184.73.122.162. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 30, 1897

THE PATHOGENESIS OF GOUT.

Author Affiliations

CHICAGO, ILL.

JAMA. 1897;XXVIII(5):212-218. doi:10.1001/jama.1897.02440050020001f

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Garrod demonstrated in 1848 with his thread test the presence of uric acid in the blood in gout, and basing himself upon this fact, said that in gout there was reduced capacity of the kidneys to pass uric acid; and second, that the alkalescence of the humors in gout was decreased. Charcot believed in an increased production of uric acid, caused by a functional disturbance of the liver, and Cantani thinks that the uric acid originates in the cartilages themselves, and believes that the uric acid diathesis is the consequence of disturbance in the nutrition of the cartilages, the ligaments and the tendons near the bone. The scientific researches in gout and kindred diseases had for forty years been under the ban of Garrod's discovery; all the immense work done within this span of time has been in vain, of no practical value, because now we know that not only

First Page Preview View Large
First page PDF preview
First page PDF preview
×