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The purpose of this communication is to call attention to the use of frozen carbon dioxid for the destruction of lesions in the skin or for producing a violent inflammatory reaction in such lesions. Its action, of course, depends on its intense cold and on the effect produced by freezing.
Since the idea occurred to me, eighteen months ago, I have used carbon dioxid as a destructive agent in various lesions of the skin. It furnishes a convenient and effective method of removing warts, calluses, senile keratoses and other such lesions. In the case of senile keratoses it is, I believe, an addition of some value to our methods of treatment.
I wish, however, especially to call attention to its use in certain intractable conditions, notably nevi.
The first case here reported illustrates what can be done in pigmented nevus with carbon dioxid. In this case a black hairy nevus
PUSEY WA. THE USE OF CARBON DIOXID SNOW IN THE TREATMENT OF NEVI AND OTHER LESIONS OF THE SKIN.A PRELIMINARY REPORT.. JAMA. 1907;XLIX(16):1354-1356. doi:10.1001/jama.1907.25320160032001h