In the winter of I 880, I was called to attend Mrs. R., in confinement with her fifth child. Two of her other four had been born dead; the other two, born apparently healthy, had died in convulsions at the ages of three and ten months. Both of the last had, before death, suffered from a scabby eruption, and become somewhat emaciated, but had not, as far as I could determine, been considered syphilitic. The child born at this time was, at first, apparently healthy, but, in a short time, broke out with an eruption that had the appearance of an ordinary eczema pustulosum, sum, and which affected its scalp and different parts of its body. The only other noticeable symptom was progressive emaciation.
A physician seeing the child for the first time at the age of three weeks, would have been excusable, without out the family history, in considering
BYFORD HT. OBSERVATIONS ON THE CAUSE AND TREATMENT OF INFANTILE ECZEMA AND ALLIED ERUPTIONS.. JAMA. 1885;V(12):317–318. doi:10.1001/jama.1885.02391110009001b