[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
November 9, 1907


JAMA. 1907;XLIX(19):1608-1609. doi:10.1001/jama.1907.02530190042005

By making more frequent and more thorough examination of the bony skeleton a part of the routine of autopsies, pathologists have learned recently several interesting facts concerning the development of secondary tumors of the bones that should be appreciated by clinicians. In the first place it has been found that metastatic growths in the bone occur much more frequently than has been generally supposed; E. Fraenkel1 discovered metastasis in the bones in 20 per cent, of all cases of carcinoma coming to autopsy, and Fischer-Defoy2 found bone involvement in 25.7 per cent. Had the entire osseous system been examined instead of merely the vertebral column and an occasional long bone, it is probable that these figures would have been considerably raised. Secondary carcinomas as found in the bones at autopsy are usually not conspicuous structures, and will generally escape observation unless sought for with care. In a large proportion

First Page Preview View Large
First page PDF preview
First page PDF preview