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Article
July 25, 1903

PATHOLOGY AND TREATMENT OF SMALLPOX.AN ANALYSIS OF OVER TWO THOUSAND CASES AND OF FIFTY AUTOPSIES.

Author Affiliations

Assistant to the Chair of Dermatology, Syphilology and Clinical Medicine and Demonstrator of Bacteriology in the Medical College of Indiana. INDIANAPOLIS.

JAMA. 1903;XLI(4):233-239. doi:10.1001/jama.1903.04480010019005
Abstract

CLASSIFICATION.  It is not my intention to discuss in detail the problem of the pathology of smallpox, but only to utilize in so far as practical the knowledge acquired by personal observation and autopsy in the treatment of this disease. The subject of the pathology of smallpox is in itself one of large scope and bearing, and worthy of single effort, Inasmuch as the tendency of medicine at the present day is to build the treatment of disease on the knowledge acquired of anatomic defects, it seems consistent to group the two headings.The pathology of smallpox comprises at least three distinct considerations: First, the conditions arising from the poisonous influences of the variolous contagion itself (mainly purely speculative and relating to black smallpox). Second, the conditions arising from the maturation stage; and third, the incidental complications and sequelæ. In the latter class are considered boils, abscesses, phlegmonous conditions, erysipelas,

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