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The increasing number of reports of this disease, the contentions over its surgical or medical treatment and opposing views as to its nature and cause, it is to be hoped, will soon lead to a few careful and through anatomic studies. The earlier conception of its fundamental congenital genesis, at least for the majority of cases, has been abandoned; this is mainly due to the absence of symptoms for varying periods after birth. In the 23 cases collected by Pritchard in 1900 there were some in which symptoms were not observed until the infants were several months old. The absence of any reports of increased connective tissue in the histologic studies of the hypertrophied pylorus is also to some extent opposed to the intrauterine development of the condition. In a small number of cases, a prenatal stenosis at the pylorus may occur, as it does in other parts of the
INFANTILE HYPERTROPHIC STENOSIS OF THE PYLORUS.. JAMA. 1903;XLI(4):262-263. doi:10.1001/jama.1903.04480010048013