A few months ago we expressed some opinions on the value of salvarsan, based in part on our own experience and in part on that of others. Our present communication is a detailed account of work that has been done during the past eight months, and the conclusions drawn are based entirely on our own experience.
The greater part of our observations have been made at the New York Skin and Cancer Hospital in the service of Dr. George Henry Fox. At the time of writing, 128 injections have been given to 100 selected patients. The first ten patients were treated by the subcutaneous method (Wechselmann), after which intramuscular injections of an alkaline solution (Lesser method) were tried in twenty cases. Later, the intravenous method was employed in sixty-nine cases and intramuscular injections of an oily suspension in twenty-nine cases. The treatment was repeated in twenty-one of our patients, three
FOX H, TRIMBLE WB. EIGHT MONTHS' EXPERIENCE WITH SALVARSAN AT THE NEW YORK SKIN AND CANCER HOSPITAL. JAMA. 1911;LVII(21):1675–1681. doi:10.1001/jama.1911.04260110175007