Among what may be termed the triumphs of modern medical investigation, there are probably none more interesting historically or more illuminating in their results than investigations in external and internal respiration.
Although physiologists have greatly enlarged our views and knowledge of the subject, respiratory phenomena do not enlist the interest of clinical men so much as the growing knowledge of respiratory physiology warrants.
Physiology of respiration involves a number of problems, viz.: the lung as an aerating organ, the mass movement of blood, the partial pressure of carbon dioxid and oxygen in alveolar air and circulating blood, products of metabolism and finally the nervous control of respiration which may be modified by alterations in the bulbar respiratory center cerebral cortex and pulmonary branches of the vagus.
I propose to describe some alterations in the nervous control of respiration which occur in several diseases we commonly see, tabes dorsalis, sclerosis of
HOOVER CF. DISTURBANCES OF RESPIRATION DUE TO NUCLEAR AND INFRANUCLEAR DISEASE. JAMA. 1911;LVII(22):1733-1737. doi:10.1001/jama.1911.04260110233001