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Article
December 21, 1907

THE INFLUENCE OF FOOD AND OF EPITHELIAL ATROPHY ON THE MANIFESTATIONS OF SACCHARO-BUTYRIC INTESTINAL PUTREFACTION.

Author Affiliations

NEW YORK CITY.

JAMA. 1907;XLIX(25):2077-2082. doi:10.1001/jama.1907.25320250029001e
Abstract

THE RESULTS OBTAINED.  These results indicate that the human intestine may contain spore-forming bacteria capable of splitting olive oil to a very large extent. In the case of the human material employed for inoculation, it is reasonable to suppose that the spore-forming putrefactive bacteria were responsible for the high degree of fat-splitting observed. This fact is the more noteworthy, as previous observers have found that the human feces in twenty-four hours split the fat from butter or milk to a considerably less extent (8 to 12 per cent. in experiments by Fr. Müller). It has been supposed by some writers that the high degree of fat-splitting observed in the human intestine, despite the exclusion of the pancreatic juice and the bile, may be in part referable to a vicarious secretion of pancreatic enzymes into the small intestine.In view of the results above reported, this explanation appears to me quite

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