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The author endeavors to collect and review the scattered literature on thyroid. He places the symptoms and results of thyroid insufficiency and connects the deficient secretion of the thyroid with a number of diseased conditions, the relation of which is certainly not well known to the medical profession in general. His first chapter deals with the relation of thyroid deficiency to rickets and dental caries. In the second chapter he investigates the causes for the increasing prevalence of these diseases depending on thyroid insufficiency. These he sums up in three categories: (1) spread of measles and other "minor" infectious complaints through increased educational movements; (2) loss of calcium salts in food and water, operating partly per se, but chiefly by adverse influence on thyroid activity; (3) decrease of thyroid activity due to loss of function entailed by evasion of maternity or lactation, or both.
He regards the thyroid as a
Theory and Practice of Thyroid Therapy.. JAMA. 1911;LVII(25):2020. doi:10.1001/jama.1911.04260120210037