The most important contribution to the prophylaxis of cerebrospinal meningitis is the knowledge, recently acquired, that the causative organism—the Diplococcus intracellularis meningitidis of Weichselbaum—has its natural habitat in the nose and throat and that the disease is spread through the medium of an intermediary or healthy carrier. With these two facts well established, a formidable point of vantage in combating the spread of the infection is obtained.
The Diplococcus intracellularis meningitidis first obtains lodgment in the throat or the nasopharyngeal cavities, more frequently in the latter, these localities representing the original sites of infection and proliferation. As to the route the infection pursues from these points to the meninges, there is a diversity of opinion. A consideration of these differences will be of assistance and for this reason they will be treated briefly.
Exposure of the sinuses by splitting the skull sagitally fails to reveal to the naked
KING HD. THE PROPHYLAXIS OF CEREBROSPINAL MENINGITISWITH SOME OBSERVATIONS AS TO CARRIERS. JAMA. 1912;LVIII(6):403–405. doi:10.1001/jama.1912.04260020087006