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September 26, 1903


JAMA. 1903;XLI(13):790. doi:10.1001/jama.1903.02490320030006

Koch's experiments on the immunization of cattle against tuberculosis, which have been carried on for two years past, are reported by Neufeld.1 The results of these experiments, the latter asserts, confirm Koch's statement of the non-identity of human and bovine tuberculosis, in fact, give the key to immunization research. It was possible in animals which were only capable of being affected by one toxin to produce immunity to this toxin by previous treatment with the other. The experiments were made with goats and asses, and later carried on in cattle. Some curious results in regard to the toxic dose of extract of tubercle bacilli were noted, but these will be described more fully in the abstract of the paper to be given in our next number. They find it impossible to produce immunity in guineapigs. The problem of producing immunity in man is somewhat different, but the results of

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