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Article
March 30, 1912

THE EFFECTS ON THE HEART OF "SOLUBLE DIGITOXIN, CLOETTA"

JAMA. 1912;LVIII(13):921-925. doi:10.1001/jama.1912.04260030319007
Abstract

An article by Benjamin Moore, professor of biochemistry at the University of Liverpool, appearing recently,1 on this subject, is based partly on experimental evidence, and it is the purpose of the present paper to discuss the evidence submitted.

In calling attention to the need, so universally felt, for more exact preparations of digitalis, Moore says:

Although digitalis is one of the most valuable of all our cardiac drugs, its therapeutic administration still lies at the stage of development, comparable to that of the use of decoctions of cinchona bark before the isolation of quinin.

The physician is still, unfortunately, forced to prescribe an infusion or tincture of digitalis leaves prepared on the same principle as a cup of tea, although the toxicity of the product so administered may vary as much as that of the domestic beverage.

It is well known that digitalis leaves do deteriorate and become moldy

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