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March 30, 1912

Ueber Neurorezidive nach Salvarsan und nach Quecksilberbehandlung.

JAMA. 1912;LVIII(13):961. doi:10.1001/jama.1912.04260030359041

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This work of Benario's is a piece of special pleading in behalf of salvarsan, its object being to show that the disquieting, not to say alarming, accidents to the nervous system arising in connection with the use of salvarsan are due to syphilis and not to salvarsan. His method of procedure is to collect the "neurorecidives" occurring under mercurial treatment reported in the literature and set them over against the nerve disturbances reported following salvarsan. The result is not convincing as regards the harmlessness of salvarsan to the nervous system, but it is a monument of laborious defense and of fidelity to the cause of salvarsan.

Benario, with painstaking thoroughness, defends salvarsan from the charge that it causes toxic injury to the central nervous system either directly or by causing a lessened resistance in these nervous structures to the attack of the Spirochœta pallida. By comparing case histories of 122

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