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April 20, 1912


JAMA. 1912;LVIII(16):1219. doi:10.1001/jama.1912.04260040235025

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To the Editor:  —We have read with great interest the editorial on the reliability of digitalis and ergot preparations in The Journal, March 9, p. 705, which, however, we find to be misleading, if not unjust, and for several reasons.With regard to digitalis preparations the editorial mainly refers to investigations carried out by Hale, published in Bulletin 74 of the Hygienic Laboratory, and it states that Hale concluded that "the proprietary preparations for which reliability and permanence were claimed in reality were not only unreliable, but also in some cases practically worthless"; further that "in fact, it almost looked as if the biologic assays of this class of preparations had been largely a matter of printer's ink."The editorial speaks so generally of "proprietary preparations for which reliability is claimed" that it must lead one to assume that all of the drugs investigated by Hale were found to be

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