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The author holds in this essay that "mercury in small doses is a tonic, because under it the general vitality is improved and the number of red blood cells increased."
Twenty years have passed since Professor Keyes gave his views on this subject, and we think he has a right to claim that his position has been fully sustained, and to him more than to to any other one man has been due the disappearance of professional prejudice against the use of mercury, in many forms of the disease.
The Tonic Treatment of Syphilis.. JAMA. 1896;XXVII(16):876. doi:10.1001/jama.1896.02430940046022