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October 17, 1903


JAMA. 1903;XLI(16):969-970. doi:10.1001/jama.1903.02490350025007

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One of the first results of the small grants given by the American Medical Association to promote scientific research is embodied in the article by Gustav F. Ruediger in the present issue of The Journal. It appears that pathogenic streptococci have the power, under certain conditions, of producing a substance that causes laking and destruction of red corpuscles (hemolysis). In the case of rabbits, this laking occurs during life in the course of streptococcus infections. In view of the frequency and of the gravity of streptococcus infections in man, this being probably our most frequent secondary infection and certainly the principal element of danger to life in the course of smallpox and scarlet fever, any definite advance in our knowledge of the pathogenic action of streptococci is most desirable. Now the production by streptococci of a definite poison to red corpuscles explains very satisfactorily the grave anemia that commonly develops

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