It is not my purpose to enter here into a discussion of the extent of the value of the diazo reaction in clinical work. I take it for granted that physicians are all making use of the test for this reaction, and that like myself they have found it of much help, particularly in the diagnosis of typhoid fever.
During the past year, a statement from an Italian source appeared in the medical press of this country to the effect that certain drugs when ingested will cause the urine to react positively to the usual diazo test. An editorial in a leading medical journal seemed to take this statement for granted. This has induced me to institute some observations on this subject in the wards of the Davis Memorial Hospital, the details and results of which I herewith submit.
—A man aged 40, recovering from a compound fracture
GOLDEN WW. DRUGS AND THE DIAZO REACTION.. JAMA. 1905;XLV(13):892-893. doi:10.1001/jama.1905.52510130012001b