The epidemic of sore throat that prevailed in Chicago during the past winter, especially late in December and in January, was revealed in its more serious aspects by the marked increase in the number of complicating infections of various kinds. This was especially noticeable at many of the hospitals and was also commonly noted by physicians in their regular practice. My interest was especially aroused by the occurrence of a number of deaths at St. Luke's Hospital, and autopsy on three such cases revealed, among other lesions, acute septic peritonitis, from all of which a streptococcus was isolated in pure culture.
These deaths occurred late in the month of January within a period of about ten days and the histories in all cases revealed the fact that the infection began as a sore throat or an acute tonsillitis. A number of other fatal cases occurred at about the same time
DAVIS DJ. BACTERIOLOGIC STUDY OF STREPTOCOCCI IN MILK IN RELATION TO EPIDEMIC SORE THROAT*. JAMA. 1912;LVIII(24):1852-1854. doi:10.1001/jama.1912.04260060201009