October 21, 1905


JAMA. 1905;XLV(17):1250. doi:10.1001/jama.1905.02510170042003

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Since Jürgens in 1884 described the peculiar changes in the liver in puerperal eclampsia, a large number of carefully studied cases has accumulated, so that it may be said that the pathologic anatomy of the disease now is fairly well understood. Perhaps the most active observer in this field has been Schmorl in Dresden, who has studied no less than 73 cases.

Harbitz, who recently reviewed all this work, points out that the most important, essential, anatomic changes in eclampsia concern the blood, in which there is more or less laking of the corpuscles and coagulation with the formation of thrombi and emboli; associated with and partly, at least, dependent on these alterations are hemorrhages, infarctions and necroses. The liver of eclampsia, with the congestion, infarctions and degenerations, presents a picture that is hardly ever seen in any other diseased condition. It is important to note that acute or chronic

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