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October 21, 1905


JAMA. 1905;XLV(17):1251. doi:10.1001/jama.1905.02510170043005

Considerable interest has arisen lately over the relation of various inflammatory and necrotic processes and fusiform bacilli, associated, as a rule, with long spirilla. Many articles have appeared on this subject in foreign literature, but it is only within the last three years that cases have been reported in America. The organisms have been found, usually together, in ulceromembranous angina (Vincent's) and stomatitis, pyorrhea alveolaris, noma, hospital gangrene, appendicitis, gangrenous ulcers of the penis, bronchiectasis, periostitis, abscess of the leg and cerebral abscess. Although it has not been absolutely proved that these organisms are the exciting agents in these pathologic lesions, it seems probable that they are. The bacilli have been isolated recently in pure culture. The spirilla have been cultivated, but only in mixed cultures. By further study of these organisms their relation to these various lesions may be settled.

Wright1 has advanced the theory that these organisms

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