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Other than that the spleen plays, some part in the destruction of old blood-corpuscles and the generation of new, little is known concerning the function of this organ. That it is somehow affected in the course of many of the infectious diseases is apparently shown by the frequency with which it undergoes enlargement of size in conjunction therewith. Various hypotheses have been propounded as to the nature and the purpose of the alterations that take place, but none has thus far withstood the tests of experimental inquiry. It is therefore a source of satisfaction to note that the subject has recently been taken up and given consideration on a generous scale by Blumreich and Jacoby (Berliner klinische Wochenschrift, May 24, 1897, p. 444) at the Second Medical Clinic of the University of Berlin. These observers made a careful and scientific study of the influence exerted upon the susceptibility of guinea
THE ROLE OF THE SPLEEN IN INFECTIOUS DISEASES.. JAMA. 1897;XXIX(3):135-136. doi:10.1001/jama.1897.02440290041005