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The biology of the malarial parasite is one of the most interesting subjects in modern medicine, the accurate understanding of which is rendered exceedingly difficult to the average practitioner by reason of the conflicting opinions of competent observers as to its life cycle, the function of its various forms and their pathogenic relationship to the various clinical malarial manifestations. The segmentation of the intra-corpuscular parasites, their escape into the plasma of the blood and their reappearance as fresh hyaline bodies in the red corpuscles as described by Golgi, is believed to be the method of reproduction. The evidence that this is the method of reproduction rests upon the very great resemblance between the antecedent and resultant hyaline bodies, and further upon their identity with the fresh hyaline forms that make their appearance just at this time in other red blood corpuscles.
This theory of reproduction is rendered somewhat hypothetic by
WOODSON RS. A BRIEF CONTRIBUTION TO THE BIOLOGY OF THE MALARIAL PARASITE.. JAMA. 1897;XXIX(6):268-269. doi:10.1001/jama.1897.02440320012001e