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Article
December 19, 1903

THE DIPHTHERIA BACILLUS AS A CAUSE OF GANGRENE OF THE SKIN.

JAMA. 1903;XLI(25):1545-1546. doi:10.1001/jama.1903.02490440035010
Abstract

In 1902, Sailer3 reported two cases of gangrenous stomatitis following typhoid fever, in which the bacillus of diphtheria was found in the gangrenous patches. One of his patients, a boy, aged fourteen years, died in spite of the administration of 12,000 units of antitoxin; the other patient, a girl, aged eight years, recovered after the use of antitoxin. The bacillus of diphtheria has been found by several other observers in cases of noma of the mouth, as well as of the vulva. It seems, however, that noma is not the only gangrenous affection that may follow infection with this bacillus. Bernard and Jacob4 have recently reported the case of a soldier, aged twenty-five years, who presented two furuncles on his left thigh. In a few days these boils opened and discharged, but the wounds, instead of healing, became larger, spread and appeared gangrenous, so that the patient had

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