Although the use of phenolsulphonephthalein in estimating kidney function is of only a few years' standing, it is to-day probably the most accurate index of renal elimination which we possess. It has been put to test all over the world and in all classes of cases with a resulting uniform praise of its accuracy, being considered superior to a chemical and microscopic examination of the urine in showing the actual work that the kidneys are doing.
Geraghty says that albumin and casts are no index of the severity of a kidney lesion, being present frequently in marked degree when the pathologic change in the kidney is slight, while on the other hand severely damaged kidneys may be present when there are very few abnormal constituents in the urine, whereas the phenolsulphonephthalein test, according to him, will practically always tally with the kidney changes. As a demonstration of this fact, I
BLOCK FB. THE EFFECT OF OPERATION ON KIDNEY EXCRETION AS INDICATED BY THE PHENOLSULPHONEPHTHALEIN TEST. JAMA. 1914;LXII(17):1309-1310. doi:10.1001/jama.1914.02560420015008