[Skip to Content]
[Skip to Content Landing]
Article
October 9, 1897

TWO CASES OF TRISMUS NASCENTIUM SUCCESSFULLY TREATED BY TETANUS ANTITOXIN.

Author Affiliations

PROFESSOR OF DISEASES OF CHILDREN AND CLINICAL MEDICINE, BEAUMONT MEDICAL COLLEGE. ST. LOUIS, MO.

JAMA. 1897;XXIX(15):727. doi:10.1001/jama.1897.02440410015002d

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Within the past five weeks I have had an opportunity of experimenting with tetanus antitoxin in the treatment of two cases of trismus nascentium. This disease of infancy has been almost uniformly fatal and, notwithstanding the fact that all kinds of treatment have been used, has thus far resisted every measure.

On learning of the successful treatment of tetanus in the adult by the serum treatment, I determined to try the same remedy for the infantile disease. By reason of the extreme youth of the patient one has no guide as to the quantity of the serum to be used. As will be seen in the first case, knowing that the child would die under the ordinary plan of treatment, a large dose was used in the beginning, considering the weight of the child as compared with that of the adult, in which a full bottle is usually administered.

In

First Page Preview View Large
First page PDF preview
First page PDF preview
×