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While acute articular rheumatism presents the general clinical features of an infectious disease, bacteriologic confirmation is yet wanting. A number of observers have found in the blood, the transudates and the secondary lesions of patients suffering from this disease different micro-organisms to each of which specific etiologic significance has been attached; but the evidence is not of such a nature as to be accepted as conclusive. On the other hand in many instances the results of bacteriologic examination have been of a negative character. Attributing these discrepancies to the use of varying and perhaps unsuitable culture-media Riva of Parma ( Centralblatt für Innere Medicin, Aug. 14, 1897, p. 825) undertook to harmonize the resulting diversity of opinion by using as a culture-medium fluid obtained from the tissues in which it may be supposed that the hypothetic specific micro-organism resides. With this end in view he secured fresh joints from horses, which
THE ETIOLOGY OF ACUTE ARTICULAR RHEUMATISM.. JAMA. 1897;XXIX(16):808. doi:10.1001/jama.1897.02440420042005