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Article
February 3, 1906

CHORIONEPITHELIOMATOUS PROLIFERATIONS IN TERATOMATA, ESPECIALLY IN THOSE OF THE TESTICLE; WITH THREE NEW CASES.

Author Affiliations

NEW YORK; From the Department of Pathology of the College of Physicians and Surgeons, Columbia University.

JAMA. 1906;XLVI(5):343-350. doi:10.1001/jama.1906.62510320029001g
Abstract

3. HYDATIDIFORM PROLIFERATIONS IN TERATOMATA. 

CASES IN THE MALE.  The preceding cases, many of them consisting of testicle tumors in which chorionepitheliomatous proliferation with teratomatous elements are demonstrable, are sufficiently numerous, similar and well authenticated to be accepted as a distinct and recognized variety of tumor. Schlagenhaufer has, in addition, described what he considers a modification of these neoplasms, which bear a similar relation to chorionepithelioma of the testicle that hydatid moles bear to chorionepithelioma of the uterus. This author has personally reviewed the case reported by Karl Breus72 in 1878, and re-examined the material, also collecting five cases from the literature. All these cases have certain features in common. A primary testicle tumor is present in all; in most of them the testicle tumor is evidently a teratoma; in one only (Breus' case) do parts of the metastases resemble chorionepitheliomatous tissue. In all, metastatic extension into the large

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