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February 3, 1906


JAMA. 1906;XLVI(5):362-363. doi:10.1001/jama.1906.02510320048005

Recently1 we called attention to the views of A. E. Wright of London regarding the treatment of diseases due to endotoxic bacteria by means of vaccines. In a recent article Wright2 gives his latest views regarding this method of treatment and refers to his results in tuberculosis.

It will be remembered that Wright's method of administering bacterial vaccines, i. e., sterilized and standardized suspensions of micro-organisms, based on the fact that in bacterial diseases there are times when the body resistance is lower than normal, and times when it is higher. Wright measures the resistance to the particular infecting germ, in tuberculosis, for example, to the tubercle bacillus, by submitting a standardized culture of the organism to the action of the living leucocytes of the individual whose blood he is testing. The particular antibacterial element measured by Wright's method is one which injures the bacteria so that they

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