Of all branches of medicine, that represented by diseases of the nervous system has perhaps been least influenced by the science of bacteriology. In a minor way it has felt the effect of microbic theories, but until now, so far as my knowledge extends, no attempt has been made to explain more rationally upon this basis some of the vexed questions of the etiology of many nervous affections.
I shall undertake to bring forward a newer origin of many diseases of the nervous system. In these days of scientific medicine our profession rightfully demands proofs. I am aware that I have little incontestable proof in support of this theory to offer at the present time. Nevertheless, I think considerable evidence for the toxic origin of many affections of which the etiology has long been a source of doubt will be shown.
In speaking of the toxic origin of nervous diseases
STERNE AE. TOXICITY AS AN ETIOLOGY OF NERVOUS DISEASES.. JAMA. 1895;XXV(3):103-106. doi:10.1001/jama.1895.02430290017001f