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March 17, 1906


Author Affiliations


From the service of Dr. James Hendrie Lloyd in the Philadelphia Hospital.

JAMA. 1906;XLVI(11):802-803. doi:10.1001/jama.1906.62510380040003d

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The following case of Friedreich's ataxia presents nearly all the symptoms of the disease, according to the synopsis of Soca and Ladame, except the familial feature. Although this familial tendency is usual, cases in which direct inheritance can be traced are rarely observed. The cases of Gowers, Osler and Carre are instances. Isolated cases are far from rare and have been reported, showing nothing more of note than the sporadic occurrence.

Patient.  —J. M., aged 24, single white, male.

Family History.  —Mother is living, aged 60. Father died as the result of an accident at the age of 55. Parents were not related, and no nervous disease of any nature is known in the family. The father was an alcoholic. Alcoholism in parents has been spoken of as an important etiologic factor; Friedreich in his first cases insisted on the causal relationship of alcoholism in parents to this disease. The

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