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New Richmond, Ohio, March 16, 1906.
To the Editor:
—In 1874 I read, at a meeting of the American Medical Society in Cincinnati, my translation of an article from "Volkmann's klinische Vorträge," written by Jurgenson in 1872, in which he advocates the use of large doses of quinin in the treatment of pneumonia in conjunction with cold water baths. He gave from 25 to 40 grains at one dose, or if this was not advisable owing to an idiosyncrasy of the patient, he divided the dose in three or four equal portions, giving each at intervals of fifteen or twenty minutes, but so that the entire quantity was taken within an hour, or the reduction of temperature would not take place. I followed out this quinin treatment for two years, but found that it did not influence the course of pneumonia either favorably or otherwise, and it was often followed
Erdman RF. Quinin in Pneumonia.. JAMA. 1906;XLVI(12):901. doi:10.1001/jama.1906.02510390059018