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Dover, N. H., Feb. 28, 1906.
To the Editor:
—In a pamphlet sent out by the manufacturers of Argyrol I find the following statement: "Argyrol is the only silver salt that does not permanently stain the conjunctiva. It may be used with safety by patients themselves, as often as required."Last week a patient appeared in my office who had been using a 10 per cent, solution of Argyrol in the left eye for nearly a year. It was originally prescribed by a competent oculist, but, of course, with the intention that it should only be used for a short time. I took pains to hunt up the original prescription to be sure that it was Argyrol.In this case the bulbar conjunctiva, the caruncle, and the lining of the lid were as badly stained as from the prolonged use of a solution of nitrate of silver.
Flanders LW. Staining of Conjunctiva by Argyrol.. JAMA. 1906;XLVI(12):901. doi:10.1001/jama.1906.02510390059019