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March 24, 1906

Uric Acid. The Chemistry, Physiology and Pathology of Uric Acid and the Physiologically Important Purin Bodies, with a discussion of the Metabolism in Gout.

JAMA. 1906;XLVI(12):906. doi:10.1001/jama.1906.02510390064027

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This little volume from the laboratory of physiology and chemistry of the Harvard Medical school, constitutes the most complete literary review of the uric acid question that so far has been published. The pure chemistry of uric acid and of the whole group of purin bodies, the solubility of uric acid and the urates, the physiology of uric acid, including its formation and decomposition in the body, the effects of drugs on the excretion and solubility of uric acid, and finally, its pathology and metabolism in gout and lithemia, are all very carefully discussed. The facts collected, therefore, represent practically all that is known in regard to the uric acid subject, and the author deserves immense credit for his diligent search through innumerable publications for the material that forms the basis of his book.

The conclusions that the author draws from his collected data, including some experiments of his own

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