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The fact that many persons use spirits to excess at intervals, or in moderation for a life time, and from superficial observation are apparently no worse, is both misleading and dangerous. In one case it conveys the impression that spirits are harmless in small quantities, and occasional excesses are of little injury from which restoration quickly follows. In the second case the danger of repeated pathologic disturbances are masked until organic changes take place, and most serious results follow, that are not apparent except in other departures from health.
The so-called moderate user of spirits when examined critically appears differently from what he himself or friends suppose. His fancied vigor and mental health is an illusion. His freedom from pain or discomfort is the work of narcotism and diminished nerve sensibilities. Constant dulling of the senses by the steady use of small doses of alcohol removes all warnings of danger,
CROTHERS TD. ALCOHOLIC INTOLERANCE AND PREDISPOSITIONS.. JAMA. 1895;XXV(13):515-517. doi:10.1001/jama.1895.02430390001001