However warm the discussion as to the dietetic or medicinal value of alcohol, there is no difference of opinion with regard to the pronounced and profound toxic effects to which this substance is capable of giving rise. These may be insidious and appear especially in the liver, kidneys and vascular system, or they may be acute and by preference involve the nervous system. In the latter event, the cerebral cortex and the peripheral nerves suffer most commonly, as manifested by delirium tremens and polyneuritis, respectively. The factors that determine the one or the other set of phenomena are as yet unknown, and it is not rare for alcoholic neuritis to be associated with varied abnormal mental phenomena.
As a result of a study of 17 cases of alcoholic intoxication, in conjunction with an analysis of the literature of the subject, Dr. Isador Coriat1 arrives at the conclusion that the
MENTAL SYMPTOMS ASSOCIATED WITH ALCOHOLIC NEURITIS.. JAMA. 1906;XLVII(3):208–209. doi:10.1001/jama.1906.02520030050006