The importance of the study of the pathology of the oral cavity in connection with the treatment of systemic diseases is obvious, and he who is ignorant of its teachings is not only unjust to his patients, but must be regarded as a hindrance to the progress of his profession.
We often hear the study of micro-organisms referred to as the new or germ theory, and, unfortunately, not only by those who deal in glittering platitudes of which they are ignorant, but often by members of our own profession who make statements which cause us to feel that this most important part of their technical education has been neglected. The great Roman author, Varro, in his writings during the first century before Christ, called the attention of the world to the fact that some indefinable, invisible, living organisms were responsible for certain diseases and especially for those of an epidemic
POWER JE. THE RELATION OF SYSTEMIC DISEASES TO THE CONDITIONS OF THE ORAL CAVITY.. JAMA. 1906;XLVII(5):334-338. doi:10.1001/jama.1906.25210050018002c