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August 4, 1906

TRYPANOSOMA DISEASE.

JAMA. 1906;XLVII(5):367. doi:10.1001/jama.1906.02520050051010

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Abstract

The recent death of an English Army surgeon from accidental inoculation with the germ of the African sleeping sickness has excited considerable interest, especially in connection with other instances demonstrating that Europeans are not immune to this widely extending African plague. Recent investigations by Dr. F. W. Mott,1 of the pathologic laboratory of the London County asylums, throw considerable light on the subject of trypanosoma disease in general and are at least suggestive as regards the pathologic processes in that worldwide scourge, syphilis. He examined the microscopic changes in the nervous system of a horse dying from dourine or mal de coit, which is caused by a trypanosoma and has many resemblances to syphilis, which we are now coming to believe is due to the Spirochæta pal-lida. Comparative examinations of the tissues of the central nervous system in this disease and in sleeping sickness seem to show that

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